Validation of the BCIS CHIP Score in chronic total occlusion percutaneous coronary intervention
Recommended Citation
Rempakos A, Alexandrou M, Mutlu D, Choi JW, Poommipanit P, Khatri JJ, Young L, Jefferson B, Gorgulu S, Jaffer FA, Chandwaney R, Davies R, Benton S, Alaswad K, Azzalini L, Kearney KE, Krestyaninov O, Khelimskii D, Dattilo P, Reddy N, Abi-Rafeh N, Elguindy A, Goktekin O, Rangan BV, Mastrodemos OC, Al-Ogaili A, Sandoval Y, Burke NM, Brilakis ES, and Basir MB. Validation of the BCIS CHIP Score in chronic total occlusion percutaneous coronary intervention. Catheter Cardiovasc Interv 2024; 103(6):856-862.
Document Type
Article
Publication Date
5-1-2024
Publication Title
Catheterization and cardiovascular interventions
Abstract
BACKGROUND: The complex high-risk indicated percutaneous coronary intervention (CHIP) score is a tool developed using the British Cardiovascular Intervention Society (BCIS) database to define CHIP cases and predict in-hospital major adverse cardiac or cerebrovascular events (MACCE).
AIM: To assess the validity of the CHIP score in chronic total occlusion (CTO) percutaneous coronary intervention (PCI).
METHODS: We evaluated the performance of the CHIP score on 8341 CTO PCIs from the Prospective Global Registry for the Study of Chronic Total Occlusion Intervention (PROGRESS-CTO) performed at 44 centers between 2012 and 2023.
RESULTS: In our cohort, 7.8% (n = 647) of patients had a CHIP score of 0, 50.2% (n = 4192) had a CHIP score of 1-2, 26.2% (n = 2187) had a CHIP score of 3-4, 11.7% (n = 972) had a CHIP score of 5-6, 3.3% (n = 276) had a CHIP score of 7-8, and 0.8% (n = 67) had a CHIP score of 9+. The incidence of MACCE for a CHIP score of 0 was 0.6%, reaching as high as 8.7% for a CHIP score of 9+, confirming that a higher CHIP score is associated with a higher risk of MACCE. The estimated increase in the risk of MACCE per one score unit increase was 100% (95% confidence interval [CI]: 65%-141%). The AUC of the CHIP score model for predicting MACCE in our cohort was 0.63 (95% CI: 0.58-0.67). There was a positive correlation between the CHIP score and the PROGRESS-CTO MACE score (Spearman's correlation: 0.37; 95% CI: 0.35-0.39; p < 0.001).
CONCLUSIONS: The CHIP score has modest predictive capacity for MACCE in CTO PCI.
Medical Subject Headings
Aged; Female; Humans; Male; Middle Aged; Chronic Disease; Coronary Occlusion; Decision Support Techniques; Percutaneous Coronary Intervention; Predictive Value of Tests; Registries; Reproducibility of Results; Risk Assessment; Risk Factors; Time Factors; Treatment Outcome
PubMed ID
38629740
Volume
103
Issue
6
First Page
856
Last Page
862
