Coronary Microvascular Dysfunction: A Guide for Clinicians

Document Type

Article

Publication Date

9-1-2024

Publication Title

The American journal of medicine

Abstract

Dysfunction of the coronary microvasculature has become increasingly recognized as an important mechanism of myocardial ischemia in patients without obstructive coronary artery disease. The causes and management of coronary microvascular dysfunction remain poorly understood and are still largely based on extrapolation of epicardial coronary artery disease data. Quantification of myocardial blood flow and flow reserve have improved diagnosis, though important questions remain. In this review, we explain current understanding of the spectrum of pathophysiology of coronary microvascular dysfunction, summarize current diagnostic techniques to assess for coronary microvascular dysfunction, and appraise the limited data on management options specifically for patients with coronary microvascular dysfunction.

Medical Subject Headings

Humans; Coronary Circulation; Microcirculation; Microvessels; Coronary Vessels; Myocardial Ischemia; Coronary Artery Disease

PubMed ID

38723930

ePublication

ePub ahead of print

Volume

137

Issue

9

First Page

810

Last Page

817

Share

COinS