Extrinsic outflow graft obstruction of the HeartMate 3 LVAD: A state-of-the-art review
Recommended Citation
Goldstein DJ, Kanwar M, Cowger J, Patel S, Meyer DM, Molina E, Salerno C, Elmer A, Schettle S, Teuteberg J, Pagani F, and Stehlik J. Extrinsic Outflow Graft Obstruction of the HeartMate 3 LVAD: A State-of-the-Art Review. J Heart Lung Transplant 2024.
Document Type
Article
Publication Date
7-15-2024
Publication Title
The Journal of heart and lung transplantation
Abstract
While notable improvements in survival, the incidence of hemocompatibility-related adverse events, hospitalizations, and cost have been demonstrated with the only commercially available durable left ventricular assist device, a category of pump malfunctions characterized by outflow graft obstruction has been noted with broader use and clinical follow-up of recipients of this technology. Of particular concern is the accumulation of acellular biodebris between the outflow graft and bend relief covering the outflow graft at its origin with the pump (which we term extrinsic outflow graft obstruction at the bend relief). This process tends to be insidious, occurs late in the postoperative course, can be challenging to diagnose, and can result in significant morbidity and mortality. Herein, we provide a review of this complication and outline diagnostic, treatment, and preventive strategies.
PubMed ID
39019352
ePublication
ePub ahead of print
