Exercise Training in Patients with Chronic Thromboembolic Pulmonary Hypertension and Pulmonary Arterial Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Document Type

Article

Publication Date

1-1-2025

Publication Title

Heart Fail Clin

Abstract

Of the 5 randomized controlled trials (RCTs) included, chronic thromboembolic pulmonary hypertension (CTEPH) patients constituted 20% of the overall pulmonary hypertension (PH) patient population. We did not find any RCTs that evaluated the role of exercise training in patients with CTEPH. The results of this study indicate that exercise training may be effective at improving exercise capacity, as measured by 6-min walk distance, in patients with PH. Another notable finding from this analysis is the lack of adverse events associated with exercise training, suggesting that contrary to widespread perception, exercise training is safe in CTEPH and PAH patients.

Medical Subject Headings

Humans; Randomized Controlled Trials as Topic; Hypertension, Pulmonary; Exercise Therapy; Pulmonary Embolism; Exercise Tolerance; Chronic Disease; Pulmonary Arterial Hypertension

PubMed ID

39550076

ePublication

ePub ahead of print

Volume

21

Issue

1

First Page

137

Last Page

148

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