Rapid Bioprosthetic Valve Degeneration in Carcinoid Heart Disease

Authors

Everett M. Woods, Henry Ford HealthFollow
Ziad R. Affas, Henry Ford HealthFollow
Souheil Saba, Henry Ford HealthFollow

Recommended Citation

Woods E, Affas Z, and Saba S. Rapid Bioprosthetic Valve Degeneration in Carcinoid Heart Disease. JACC Case Rep 2026;31(9):106731.

Document Type

Article

Publication Date

3-4-2026

Publication Title

JACC Case Rep

Keywords

bioprosthetic valve degeneration; carcinoid heart disease; pulmonic valve; tricuspid valve; valve replacement

Abstract

BACKGROUND: Carcinoid heart disease frequently necessitates right-sided valve replacement, but prosthesis choice remains debated.

CASE SUMMARY: A 66-year-old woman with carcinoid heart disease underwent tricuspid and pulmonic valve replacement. Within 6 months, she developed severe bioprosthetic stenosis and regurgitation, far earlier than typically reported.

DISCUSSION: After multidisciplinary review, the rapid failure was attributed to recurrent carcinoid valvulopathy. Mechanical valve replacement was considered but deferred because of patient preference and comorbidities.

TAKE-HOME MESSAGE: This case illustrates unusually rapid bioprosthetic valve degeneration in carcinoid heart disease and supports considering mechanical valves in select patients.

PubMed ID

41579127

ePublication

ePub ahead of print

Volume

31

Issue

9

First Page

106731

Last Page

106731