Aortic Stenosis Progression: Lessons From Multimodality Imaging
Recommended Citation
Jain R, Padang R, Postalian A, Dal-Bianco JP, Zweig BM, Ito S, Hodara R, Levine RA, Oh JK. Aortic Stenosis Progression: Lessons from Multimodality Imaging. Mayo Clin Proc. 2026.
Document Type
Article
Publication Date
6-12-2026
Publication Title
Mayo Clinic proceedings. Mayo Clinic
Abstract
Calcific aortic stenosis primarily affects the aging population and is associated with significant morbidity and mortality. The progression of aortic stenosis from sclerotic aortic valve to severe aortic stenosis is an active metabolic process that involves multiple signaling pathways. Multimodality imaging can assess aortic valve calcification and metabolic activity and quantify severity of disease. This review describes the clinical utility of echocardiography, cardiac magnetic resonance imaging, cardiac computed tomography, and nuclear imaging in the assessment of aortic stenosis. These imaging checkpoints may also serve as targets of clinical research trials aimed at halting the progression of aortic stenosis. This comprehensive review is based on relevant publications retrieved from a search of PubMed using the terms aortic stenosis and imaging and aortic stenosis progression and the time period of Jan. 1, 2010 to 2026.
PubMed ID
42285495
ePublication
ePub ahead of print
