The Role of Mechanical Circulatory Support Devices in Pulmonary Embolism: A Comprehensive Review

Authors

• Ahmad Jabri
• Mohamed Farhan Nasser
• Jonathan X. Fang, Henry Ford HealthFollow
• Pedro Villablanca, Henry Ford HealthFollow
• Herman Simon Kado
• Vikas Aggarwal, Henry Ford HealthFollow

Recommended Citation

Jabri A, Nasser MF, Fang JX, Villablanca P, Kado HS, Aggarwal V. The Role of Mechanical Circulatory Support Devices in Pulmonary Embolism: A Comprehensive Review. Interv Cardiol Clin. 2026;15(3):387-400.

Document Type

Article

Publication Date

7-1-2026

Publication Title

Interv Cardiol Clin

Keywords

Humans, Pulmonary Embolism, Extracorporeal Membrane Oxygenation, Ventricular Dysfunction, Right, Heart-Assist Devices, Heart Failure, Shock, Cardiogenic

Abstract

Pulmonary embolism (PE) remains a leading cause of cardiovascular mortality, particularly in its high-risk and intermediate-high risk presentations where acute right ventricular (RV) failure is the primary driver of hemodynamic collapse. This review comprehensively examines the pathophysiology of RV failure in PE, their indications based on current evidence and guidelines, practical considerations for implementation, management strategies, complications, and integration with other therapeutic modalities. We also highlight the crucial role of a multidisciplinary team and discuss future directions in this rapidly evolving field. Emphasis is placed on practical application for the interventional cardiologist.

Medical Subject Headings

Humans; Pulmonary Embolism; Extracorporeal Membrane Oxygenation; Ventricular Dysfunction, Right; Heart-Assist Devices; Heart Failure; Shock, Cardiogenic

PubMed ID

42209070

Volume

15

Issue

3

First Page

387

Last Page

400