Serotonin Syndrome Following Methylene Blue Administration for Vasoplegic Syndrome

Authors

Laura Hencken, Henry Ford HealthFollow
Long To, Henry Ford HealthFollow
Nancy Ly
Jeffrey A. Morgan

Recommended Citation

Hencken L, To L, Ly N, Morgan JA. Serotonin syndrome following methylene blue administration for vasoplegic syndrome. J Card Surg. Apr 2016;31(4):208-210.

Document Type

Article

Publication Date

4-1-2016

Publication Title

Journal of cardiac surgery

Keywords

Citalopram, Drug Synergism, Female, Heart-Assist Devices, Humans, Methylene Blue, Middle Aged, Prosthesis Implantation, Serotonin Syndrome, Serotonin Uptake Inhibitors, Severity of Illness Index, Vasoplegia

Abstract

Methylene blue (MB) has been used for additional blood pressure support in patients who develop severe, refractory vasoplegia; however, MB can induce serotonin syndrome, especially when used in conjunction with other serotonergic agents. We describe a case of serotonin syndrome in a patient who received MB for vasoplegic syndrome after left ventricular assist device implantation and discuss its presentation and management.

Medical Subject Headings

Citalopram; Drug Synergism; Female; Heart-Assist Devices; Humans; Methylene Blue; Middle Aged; Prosthesis Implantation; Serotonin Syndrome; Serotonin Uptake Inhibitors; Severity of Illness Index; Vasoplegia

PubMed ID

26934199

Volume

31

Issue

4

First Page

208

Last Page

210