Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association
Hall JL, Ryan JJ, Bray BE, Brown C, Lanfear DE, Newby LK, Relling MV, Risch NJ, Roden DM, Shaw SY, Tcheng JE, Tenenbaum J, Wang TN, Weintraub WS. Merging Electronic Health Record Data and Genomics for Cardiovascular Research: A Science Advisory From the American Heart Association. Circ Cardiovasc Genet 2016; 9(2):193-202.
Circ Cardiovasc Genet
The process of scientific discovery is rapidly evolving. The funding climate has influenced a favorable shift in scientific discovery toward the use of existing resources such as the electronic health record. The electronic health record enables long-term outlooks on human health and disease, in conjunction with multidimensional phenotypes that include laboratory data, images, vital signs, and other clinical information. Initial work has confirmed the utility of the electronic health record for understanding mechanisms and patterns of variability in disease susceptibility, disease evolution, and drug responses. The addition of biobanks and genomic data to the information contained in the electronic health record has been demonstrated. The purpose of this statement is to discuss the current challenges in and the potential for merging electronic health record data and genomics for cardiovascular research.
Medical Subject Headings
Biomedical Research; Cardiovascular Diseases; Data Collection; Electronic Health Records; Genomics; Humans; Informed Consent; Patient Care; Societies, Medical