TCT-37 Impact of LVEF on Baseline Characteristics and Outcomes in TTVR Recipients

Document Type

Conference Proceeding

Publication Date

10-28-2025

Publication Title

J Am Coll Cardiol

Abstract

Background: Severely reduced left ventricular ejection fraction (LVEF <35%) may influence outcomes in transcatheter tricuspid valve replacement (TTVR), yet data in this population remain limited. Methods: We analyzed 167 patients undergoing TTVR at a single center, stratified by LVEF <35% vs. ≥35%. Baseline characteristics, device success, length of stay (LOS), and 30-day readmission were compared using appropriate statistical tests. Results: Thirteen patients (7.8%) had LVEF <35%. Device success was slightly lower in the reduced EF group (92.3% vs. 97.4%, p = 0.293). Median LOS was similar (8.0 vs. 7.0 days, p = 0.908). Thirty-day readmission was higher in the LVEF <35% group (15.4% vs. 7.1%, p = 0.288), though not significant. Baseline characteristics showed lower BMI (24.1 vs. 27.3, p = 0.045) and higher BNP (1562 vs. 408 pg/mL, p = 0.001) in the reduced EF group. Fewer were female (30.8% vs. 63.6%, p = 0.034). [Formula presented] Conclusion: TTVR in patients with LVEF <35% is feasible, with comparable procedural success and hospital stay. These patients present with distinct clinical profiles, including lower BMI and higher BNP. Further studies are warranted to evaluate long-term outcomes in this high-risk subgroup. Categories: STRUCTURAL: Valvular Disease and Intervention: Tricuspid

Volume

86

Issue

17

First Page

B20

Last Page

B21

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