TCT-37 Impact of LVEF on Baseline Characteristics and Outcomes in TTVR Recipients

Document Type

Conference Proceeding

Publication Date

10-28-2025

Publication Title

J Am Coll Cardiol

Keywords

adult, aged, clinical article, cohort analysis, complication, conference abstract, controlled study, drug therapy, female, heart left ventricle ejection fraction, hospital readmission, hospitalization, human, length of stay, major clinical study, male, retrospective study, special situation for pharmacovigilance, surgery, tricuspid valve replacement, valvular heart disease

Abstract

Background: Severely reduced left ventricular ejection fraction (LVEF <35%) may influence outcomes in transcatheter tricuspid valve replacement (TTVR), yet data in this population remain limited. Methods: We analyzed 167 patients undergoing TTVR at a single center, stratified by LVEF <35% vs. ≥35%. Baseline characteristics, device success, length of stay (LOS), and 30-day readmission were compared using appropriate statistical tests. Results: Thirteen patients (7.8%) had LVEF <35%. Device success was slightly lower in the reduced EF group (92.3% vs. 97.4%, p = 0.293). Median LOS was similar (8.0 vs. 7.0 days, p = 0.908). Thirty-day readmission was higher in the LVEF <35% group (15.4% vs. 7.1%, p = 0.288), though not significant. Baseline characteristics showed lower BMI (24.1 vs. 27.3, p = 0.045) and higher BNP (1562 vs. 408 pg/mL, p = 0.001) in the reduced EF group. Fewer were female (30.8% vs. 63.6%, p = 0.034). [Formula presented] Conclusion: TTVR in patients with LVEF <35% is feasible, with comparable procedural success and hospital stay. These patients present with distinct clinical profiles, including lower BMI and higher BNP. Further studies are warranted to evaluate long-term outcomes in this high-risk subgroup. Categories: STRUCTURAL: Valvular Disease and Intervention: Tricuspid

Volume

86

Issue

17

First Page

B20

Last Page

B21

Find It @ Sladen

Share

COinS