THE IMPACT OF ATRIAL FIBRILLATION ON IN-HOSPITAL OUTCOMES IN PATIENTS UNDERGOINGLIVER TRANSPLANTATION USING NIS 2016-2021

Authors

• Omar S. Abdelhai, Henry Ford HealthFollow
• Ratib Mahfouz, Henry Ford HealthFollow
• Anand Maligireddy, Henry Ford Health
• Gautam Rangavajla, Henry Ford HealthFollow
• Tyler Q. Andrews, Henry Ford HealthFollow
• Ahmad Jabri, Henry Ford HealthFollow
• Muhammad Memon, Henry Ford HealthFollow
• Patrick McBride, Henry Ford HealthFollow
• Pedro A. Villablanca, Henry Ford HealthFollow
• Dawood Jamil, Henry Ford HealthFollow
• Vikas Aggarwal, Henry Ford HealthFollow

Recommended Citation

Abdelhai OS, Mahfouz R, Maligireddy A, Rangavajla G, Andrews TQ, Jabri A, Memon M, McBride P, Villablanca PA, Jamil D, Aggarwal V. THE IMPACT OF ATRIAL FIBRILLATION ON IN-HOSPITAL OUTCOMES IN PATIENTS UNDERGOINGLIVER TRANSPLANTATION USING NIS 2016-2021. J Am Coll Cardiol 2025; 85(12):94.

Document Type

Conference Proceeding

Publication Date

4-1-2025

Publication Title

J Am Coll Cardiol

Keywords

adult, aged, atrial fibrillation, case fatality rate, chi square distribution, comorbidity, complication, conference abstract, drug combination, drug therapy, female, gender, hospital charge, human, liver transplantation, major clinical study, male, medical history, morbidity, mortality, mortality rate, mortality risk, prevalence, risk factor, special situation for pharmacovigilance, therapy

Abstract

Background: The influence of atrial fibrillation (AF) on outcomes in patients undergoing liver transplantation has not been extensively investigated in the literature. This study aims to assess the prevalence of pre-transplant AF and its association with postoperative outcomes in patients undergoing liver transplantation. Methods Data from the National Inpatient Sample (2016-2021) identified liver transplant patients and their AF status. T-tests and chisquare tests compared the data. Outcomes included mortality risk, in-hospital results, and risk factors. Univariate and multivariate logistic regressions calculated odds ratios for comorbidities. Results The study identified 45,460 liver transplant patients, 3,905 of whom had AF. AF patients had a longer LOS (28.6 vs. 19.9 days, p = 0.001) and higher hospital charges ($768,558 vs. $624,364, p < 0.001). The mortality rate was also greater in AF patients (5.89% vs. 2.72%, p < 0.001), and this finding was confirmed by multivariate analysis, which showed an odds ratio of 1.54 (p < 0.001) after adjusting for age, gender, race, and comorbidities. Conclusion Our study demonstrated that liver transplant patients with a history of AF in a national cohort experienced higher mortality and morbidity rates. This finding underscores the importance for physicians to prioritize optimizing AF management in this patient group, which could help reduce complications, shorten hospital stays, and lower overall mortality. [Formula presented]

Volume

85

Issue

12

First Page

94