Study protocol for a type I hybrid effectiveness trial of strategies to prevent suicide attempts among adults recently released from jail
Recommended Citation
Wisnieski DM, Rossom RC, Weinstock LM, Johnson J, Miley K, Gaudiano BA, Benz MB, Borgert-Spaniol C, Graves HR, Norwood R, Kazan R, Starkey C, Kim H, Fletcher L, Kane S, Hu Y, Farrell Z, Strong S, Yeh HH, Miller T, Jones R, Morey K, and Ahmedani BK. Study protocol for a type I hybrid effectiveness trial of strategies to prevent suicide attempts among adults recently released from jail. Contemp Clin Trials 2025;161:108184.
Document Type
Article
Publication Date
2-1-2026
Publication Title
Contemp Clin Trials
Keywords
Humans, Adult, Suicide, Attempted, Suicide Prevention, Prisoners, Randomized Controlled Trials as Topic, Male, Female, Mass Screening, Young Adult, United States, Adolescent, Electronic Health Records, Jails, Middle Aged
Abstract
BACKGROUND: Over 20 % of all adult suicide deaths in the U.S. occur within one year following jail release. Individuals may have increased access to lethal means, be faced with numerous financial, legal, and social stressors, and encounter a resurgence of legal problems. Suicide prevention interventions have demonstrated effects. Widespread implementation of these interventions for individuals leaving jail detention could have a significant impact on national suicide rates.
METHODS: The 5S Study (Syncing, Screening, and Services for Suicide Prevention among Health & Jail Systems) aims to prevent suicide attempts among adults aged 18+ who are recently released from jail. Data from public jail release reports are synced with electronic health record (EHR) systems to enable proactive health system outreach. Those randomized to the intervention are contacted and consented, undergo a suicide risk screening and create a safety plan. Care Coordinators connect participants to health services. High risk participants, identified by the Patient Health Questionnaire (PHQ-9), are offered the Coping Long Term with Active Suicide Program (CLASP), an evidence-based suicide prevention intervention. Those randomized to control are never contacted and receive usual care. There is a waiver of consent for the control condition and a waiver of written consent for the intervention condition.
DISCUSSION: The 5S Study uses data linkage between EHRs and jails to identify and connect with those recently released from jail, a population historically at high risk. Trial results will highlight best practices for syncing these data and offering support during the transition back to the community.
TRIAL REGISTRATION: https://clinicaltrials.gov/study/NCT06506344.
Medical Subject Headings
Humans; Adult; Suicide, Attempted; Suicide Prevention; Prisoners; Randomized Controlled Trials as Topic; Male; Female; Mass Screening; Young Adult; United States; Adolescent; Electronic Health Records; Jails; Middle Aged
PubMed ID
41407099
Volume
161
First Page
108184
Last Page
108184
