Single-cell spatial profiling identifies a mucosal-like epithelial signature in Hidradenitis suppurativa tunnels

Authors

• Peter Dimitrion, Henry Ford HealthFollow
• Jesse Veenstra, Henry Ford HealthFollow
• Deangelo Ferguson, Henry Ford HealthFollow
• Ping Wang, Henry Ford HealthFollow
• Jeffrey Cruz, Henry Ford HealthFollow
• Tasneem F. Mohammad, Henry Ford HealthFollow
• Ian Loveless, Henry Ford HealthFollow
• Aamir Siddiqui, Henry Ford HealthFollow
• Iltefat H. Hamzavi, Henry Ford HealthFollow
• Li Zhou, Henry Ford HealthFollow
• Indra Adrianto, Henry Ford HealthFollow
• Qing-Sheng Mi, Henry Ford HealthFollow

Recommended Citation

Dimitrion P, Veenstra J, Ferguson D, Wang P, Cruz J, Mohammad TF, Loveless I, Siddiqui A, Hamzavi IH, Zhou L, Adrianto I, Mi QS. Single-cell spatial profiling identifies a mucosal-like epithelial signature in Hidradenitis suppurativa tunnels. JCI Insight. 2026;11(12).

Document Type

Article

Publication Date

6-22-2026

Publication Title

JCI Insight

Keywords

Humans, Hidradenitis Suppurativa, Mucous Membrane, Single-Cell Analysis, Epithelium

Abstract

Tunnels in HS have a transcriptional signature like mucosal epithelia that may contribute to inflammation in HS.

Medical Subject Headings

Humans; Hidradenitis Suppurativa; Mucous Membrane; Single-Cell Analysis; Epithelium

PubMed ID

42325093

Volume

11

Issue

12