Advanced Stage Melanoma Therapies: Detailing the Present and Exploring the Future
Recommended Citation
Luther CA, Swami U, Zhang J, Milhem M, Zakharia Y. Advanced Stage Melanoma Therapies: Detailing the Present and Exploring the Future. Crit Rev Oncol Hematol 2019; 133:99-111.
Document Type
Article
Publication Date
1-1-2019
Publication Title
Crit Rev Oncol Hematol
Abstract
Metastatic melanoma therapies have proliferated over the last ten years. Prior to this, decades passed with only very few drugs available to offer our patients, and even then, those few drugs had minimal survival benefits. Many treatment options emerged over the last ten years with diverse mechanisms of action. Further, combination regimens have demonstrated superiority over monotherapy, especially for targeted agents. Each therapeutic combination possesses different advantages and side effect profiles. In this review, we outline the United States Food and Drug Administration-approved melanoma treatment agents and therapies currently in clinical development, focusing on combination approaches.
PubMed ID
30661664
Volume
133
First Page
99
Last Page
111
