An Update on Drug-Induced Pigmentation

Authors

Amanda F. Nahhas, Henry Ford HealthFollow
Taylor L. Braunberger, Henry Ford HealthFollow
Iltefat Hamzavi, Henry Ford HealthFollow

Recommended Citation

Nahhas AF, Braunberger TL, Hamzavi I. An Update on Drug-Induced Pigmentation. American journal of clinical dermatology 2019; 20(1):75-96.

Document Type

Article

Publication Date

2-1-2019

Publication Title

American journal of clinical dermatology

Abstract

Drug-induced pigmentation accounts for up to 20% of all cases of acquired pigmentation. A thorough review of medical history and previous and ongoing medications as well as a complete skin examination can guide diagnosis. Implicated agents include alkylating/cytotoxic agents, analgesics, antiarrhythmics, anticoagulants, antiepileptics, antimalarials, antimicrobials, antiretrovirals, metals, prostaglandin analogs, and psychotropic agents, among others. Confirming true drug associations can be challenging, especially in the setting of delayed onset of pigmentation and coexisting polypharmacy.

PubMed ID

30374894

Volume

20

Issue

1

First Page

75

Last Page

96