Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature
Recommended Citation
Choudhry S, Bhatia N, Ceilley R, Hougeir F, Lieberman R, Hamzavi IH, Lim HW. Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature. Journal of drugs in dermatology : JDD 2014; 13(2):148-153.
Document Type
Article
Publication Date
2-1-2014
Publication Title
Journal of drugs in dermatology : JDD
Abstract
Polypodium leucotomos extract (PLE), derived from the tropical fern of Polypodiaceae family, has properties ranging from immunomodulatory and antioxidative to photoprotective. It is these multiple mechanisms of action, in combination with a favorable side effect profile, which makes PLE a promising adjunctive treatment for several dermatologic disorders. Studies are summarized on the use and potential applications of PLE in the treatment or management of photodermatoses, vitiligo, melasma, psoriasis, atopic dermatitis, and more recently, in minimizing infections in high-performance athletes. More data, however, with larger sample sizes are needed to confirm these benefits.
Medical Subject Headings
Administration, Oral; Animals; Dermatologic Agents; Humans; Plant Extracts; Polypodium; Skin Diseases
PubMed ID
24509964
Volume
13
Issue
2
First Page
148
Last Page
153
