Title

Role of oral Polypodium leucotomos extract in dermatologic diseases: a review of the literature.

Document Type

Article

Publication Date

2-1-2014

Publication Title

Journal of drugs in dermatology : JDD

Abstract

Polypodium leucotomos extract (PLE), derived from the tropical fern of Polypodiaceae family, has properties ranging from immunomodulatory and antioxidative to photoprotective. It is these multiple mechanisms of action, in combination with a favorable side effect profile, which makes PLE a promising adjunctive treatment for several dermatologic disorders. Studies are summarized on the use and potential applications of PLE in the treatment or management of photodermatoses, vitiligo, melasma, psoriasis, atopic dermatitis, and more recently, in minimizing infections in high-performance athletes. More data, however, with larger sample sizes are needed to confirm these benefits.

Medical Subject Headings

Administration, Oral; Animals; Dermatologic Agents; Humans; Plant Extracts; Polypodium; Skin Diseases

PubMed ID

24509964

Volume

13

Issue

2

First Page

148

Last Page

153

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