Delayed drug hypersensitivity reaction to secukinumab in a patient with hidradenitis suppurativa

Authors

Sasank Konda, Henry Ford HealthFollow
Nayha Shetty, Henry Ford HealthFollow
Ben J. Friedman, Henry Ford HealthFollow
Jesse Veenstra, Henry Ford HealthFollow

Recommended Citation

Konda S, Shetty N, Friedman B, and Veenstra J. Delayed drug hypersensitivity reaction to secukinumab in a patient with hidradenitis suppurativa. BMJ Case Rep 2022; 15(5).

Document Type

Article

Publication Date

5-17-2022

Publication Title

BMJ Case Rep

Abstract

A woman in her 30s presented to the dermatology clinic with widespread, pruritic, red papules and plaques involving the ears, trunk and extremities. The rash developed a few days after receiving her second injection of secukinumab, which was initiated for recalcitrant Hurley stage III hidradenitis suppurativa. Investigations revealed a psoriasiform drug hypersensitivity reaction secondary to secukinumab. In this report, we describe the clinical course, histopathological correlation and treatment of this rarely documented reaction.

Medical Subject Headings

Antibodies, Monoclonal, Humanized; Drug Hypersensitivity; Female; Hidradenitis Suppurativa; Humans; Psoriasis

PubMed ID

35580946

Volume

15

Issue

5