Konda S, Shetty N, Friedman B, and Veenstra J. Delayed drug hypersensitivity reaction to secukinumab in a patient with hidradenitis suppurativa. BMJ Case Rep 2022; 15(5).
BMJ Case Rep
A woman in her 30s presented to the dermatology clinic with widespread, pruritic, red papules and plaques involving the ears, trunk and extremities. The rash developed a few days after receiving her second injection of secukinumab, which was initiated for recalcitrant Hurley stage III hidradenitis suppurativa. Investigations revealed a psoriasiform drug hypersensitivity reaction secondary to secukinumab. In this report, we describe the clinical course, histopathological correlation and treatment of this rarely documented reaction.
Medical Subject Headings
Antibodies, Monoclonal, Humanized; Drug Hypersensitivity; Female; Hidradenitis Suppurativa; Humans; Psoriasis