Title

Current concepts in acne pathogenesis: Pathways to inflammation.

Document Type

Article

Publication Date

6-1-2018

Publication Title

Seminars in cutaneous medicine and surgery

Abstract

Acne is a disease of pilosebaceous inflammation. Pivotal in pathogenesis are the roles of hormones (insulin, insulin-like growth factor-1, androgens), Propionibacterium acnes, lipogenesis, and a proinflammatory lipid profile. Innate immune responses are induced through interaction with toll-like receptors and inflammasome activation initially and subsequently through adaptive immune activation. These insights into pathogenic inflammatory pathways can translate into novel therapeutic approaches for acne. Semin Cutan Med Surg 37(supp3):S60-S62 ©2018 published by Frontline Medical Communication.

PubMed ID

30192343

Volume

37

Issue

3S

First Page

S60

Last Page

S62

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