The diagnostic conundrum of acute cutaneous graft-versus-host disease: biomarkers remain elusive
Recommended Citation
Tisack A, Konda S, and Veenstra J. The diagnostic conundrum of acute cutaneous graft-versus-host disease: biomarkers remain elusive. Arch Dermatol Res 2023.
Document Type
Article
Publication Date
10-1-2023
Publication Title
Archives of dermatological research
Abstract
Hematopoietic stem cell transplantation is increasing in frequency with graft-versus-host disease affecting many recipients. When the skin is involved, biopsy is routinely performed but often does not aid in definitive diagnosis. Here, we examine a cohort of 32 patients for potential biomarkers that can aid in the diagnosis of graft-versus-host disease. Neither blood short tandem repeat testing or neutrophil-lymphocyte ratios were predictive of rash etiology in hematopoietic stem cell transplant patients. However, skin short tandem repeat testing showed promise as a predictor in a small minority of cases in this cohort.
Medical Subject Headings
Humans; Graft vs Host Disease; Biomarkers; Biopsy; Minority Groups; Skin
PubMed ID
37480519
ePublication
ePub ahead of print
Volume
315
Issue
8
First Page
2467
Last Page
2469
