Using Neuromodulators to Improve Scar Formation, Keloids, Rosacea, and Antiaging

Document Type

Article

Publication Date

9-1-2024

Publication Title

Dermatologic surgery

Abstract

BACKGROUND: Botulinum toxin A (BoNT-A) treatment has many uses in dermatology. Its mechanism of action and long-term effects for scar formation, rosacea, and antiaging are still being investigated.

OBJECTIVE: To conduct a literature review on BoNT-A to further investigate its use in scar formation, rosacea, and antiaging.

METHODS: A literature review was conducted using PubMed on botulinum toxin treatment for scar formation, rosacea, and antiaging. Studies discussing the toxin mechanism of action and treatment algorithm were included. The authors also provided their personal experience in BoNT-A use for these 3 conditions.

RESULTS: The mechanism of action of Botulinum toxin A in improving scar formation, rosacea, and antiaging is now better understood. While it is effective in the short term, little is still known about how frequently treatment needs to be repeated and if there are any long-term effects.

CONCLUSION: While in vitro studies have supporting evidence on the mechanism of action of BoNT-A on scar formation, rosacea, and antiaging, further studies are needed to identify long-term treatment effects.

Medical Subject Headings

Humans; Rosacea; Keloid; Cicatrix; Botulinum Toxins, Type A; Skin Aging; Neurotransmitter Agents

PubMed ID

39196841

Volume

50

Issue

9S

First Page

91

Last Page

91

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