61478 Pigmentation disorders in North America Results of International Survey on Pigmentation-disorders Observational Tracking [I'SPOT] study

Document Type

Conference Proceeding

Publication Date

9-1-2025

Publication Title

J Am Acad Dermatol

Abstract

Introduction and objectives: The psychological impact of pigmentation disorders (PD) remains poorly understood. This study provides information about the impact of PD on the patients' daily life. Material and methods: 48000 individuals from 34 countries participated. A self-administered online questionnaire collected demographic data, self-reported pigmentation status based on descriptions and images, as well as other information related to PD. The DLQI and PUSH-D questionnaires were also used. Data from the US and Canada (NA) were compared with those from the 32 other countries (RoW). Results: 49.6% in NA had at least one PD compared with 52.5% in RoW (p< 0.0001). 61.2% in NA compared with 59.3% were females. One third reported a previous dermatological diagnosis, with a lower proportion in NA (22.7%vs 31.6%, p=0.011). 14.4% in NA (27.2% in RoW, p<0.0001) reported an impact of PD depending on the condition. Incidences differed between conditions in NA and RoW. Only melasma, vitiligo and PIH generated similar stigma. In the NA, 31.4% vitiligo subjects reported fear compared to 44.8% of RoW subjects. Feelings of being rejected were 25.7% for vitiligo and 14.7% for melasma in NA. These figures were 29.4% for vitiligo and 22.5% for melasma in ROW. Conclusions: PD are significantly less frequent in NA than in RoW. RoW subjects were more impacted by their PD. PD impacts significantly different on the QoL, indicating psychological and social challenges. The high stigmatization calls for better support and higher awareness of PD.

Volume

93

First Page

AB71

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