61220 Analysis of patients with hidradenitis suppurativa from a large, single-center Detroit cohort: a retrospective cross-sectional study of 13,130 patients over a 27-year period
Recommended Citation
Young K, Loveless I, Su W, Veenstra J, Zhou L, Hamzavi I, Adrianto I, Mi Q. 61220 Analysis of patients with hidradenitis suppurativa from a large, single-center Detroit cohort: a retrospective cross-sectional study of 13,130 patients over a 27-year period. J Am Acad Dermatol 2025; 93:AB16.
Document Type
Conference Proceeding
Publication Date
9-1-2025
Publication Title
J Am Acad Dermatol
Abstract
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition characterized by painful nodules and abscesses. Recent studies suggest that HS has increased prevalence and disease severity among patients with skin of color, yet most epidemiological surveys focus on homogenous patient populations. Our study aimed to describe features of a large, diverse cohort of HS patients. We performed a retrospective cross-sectional study of 13,130 patients with HS over a 27-year period at a single Detroit institution. We observed a female sex bias of 3:1 across all racial/ethnic subgroups. Patients identifying as Black/African American (AA) were diagnosed at younger ages compared to White patients (37.1 years versus 39.4 years, P<0.05). In the literature, HS has been linked to several environmental factors, including obesity and smoking. In our cohort, more Black/AA females were considered clinically overweight or obese compared to White females. On the contrary, fewer Black/AA males with HS were overweight or obese compared to White males. Additionally, Black/AA patients with HS more frequently reported no smoking history compared to White patients (P<0.05). Black/AA patients also had higher rates of comorbidities, including congestive heart failure (OR=2.10; CI=1.19-3.78; P<0.05), chronic pulmonary disease (OR=1.34; CI=1.02-1.79; P<0.05), diabetes (OR=1.73; CI=1.16-2.58; P<0.05), and renal disease (OR=2.66; CI=1.67-4.34; P<0.05) compared to White patients. Furthermore, male patients were more likely to have renal disease than female patients (OR=2.62; CI=1.66-4.14; P<0.05). In conclusion, this study highlights significant differences in demographics, risk factors, and comorbid conditions among HS patients, underscoring the need for appropriate clinical study designs and improved clinical management of diverse patient populations.
Volume
93
First Page
AB16
