Clinical Effectiveness of Complementary and Alternate Therapies for Androgenetic Alopecia

Document Type

Conference Proceeding

Publication Date

7-1-2026

Publication Title

J Am Acad Dermatol

Keywords

Dermatology

Abstract

Androgenetic alopecia is the most prevalent form of hair loss in both males and females and is often associated with substantial psychological distress. The pathogenesis is multifactorial, involving genetic, hormonal, and environmental factors. Currently, the only FDA-approved medications are finasteride and minoxidil.1 However, the potential adverse effects and variable efficacy has led to increased patient interest in complementary and alternative therapies. This review synthesizes current evidence on non-pharmacologic and natural interventions for androgenetic alopecia. Physical modalities consist of low-level laser therapy, platelet rich plasma, scalp massage and acupuncture.2,3 Botanical 5-alpha reductase inhibitors include rosemary oil, pumpkin seed oil, and saw palmetto.1,4 Green tea extract, peppermint oil, and tea tree oil are examples of other natural products with different mechanisms.1 Rosemary oil, in particular, may be the most promising and cost effective natural product for androgenetic alopecia.1,5 Long-term use of finasteride and minoxidil can cause adverse effects such as decreased libido, scalp dermatitis, and pruritus.1 Comparatively, these alternative therapies are generally well-tolerated and may possess anti-inflammatory and antioxidant properties.1 Overall, there is varying scientific evidence supporting the use of these complementary and alternative therapies for androgenetic alopecia. In this review, we will further examine the properties and clinical effectiveness of these treatments.

Volume

95

Issue

1

First Page

AB106

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