Impact of Individualized Versus Weight-Based Pain Protocols on Patient Satisfaction for Patients With Sickle Cell Disease Experiencing a Vaso-Occlusive Episode

Document Type

Article

Publication Date

7-1-2025

Publication Title

Journal of emergency nursing

Keywords

Humans, Anemia, Sickle Cell, Male, Female, Patient Satisfaction, Pain Management, Adult, Emergency Service, Hospital, Pain Measurement, Clinical Protocols, Body Weight, Young Adult

Abstract

INTRODUCTION: National guidelines for the acute management of sickle cell disease vaso-occlusive episodes recommend the use of a patient-specific or a weight-based protocol. The authors compared patient satisfaction with pain management between those randomized to receive either a patient-specific or weight-based pain protocol in the COMPARE-VOE randomized control trial.

METHODS: Participants with sickle cell disease were pre-enrolled and patient satisfaction with pain management was assessed at the time of discharge from the 6 participating emergency departments. Patients were randomized to receive a patient-specific or weight-based pain protocol. The authors compared continuous variables between the patient-specific and weight-based protocols with the 2-sample t test and categorical variables by the chi-square test.

RESULTS: The authors enrolled 104 participants. Compared with satisfaction with pain management on previous ED visits, more participants in the patient-specific protocol group than the weight-based group (57.1% vs 31.8%; P = .02) were satisfied with pain management. Most who were discharged home (91.2%) felt their pain was sufficiently relieved to be discharged home.

DISCUSSION: These findings support evidence-based guidelines to manage vaso-occlusive episodes in emergency departments. Patient-specific protocols can be implemented by partnering with local sickle cell disease providers to make protocols available in the emergency department.

Medical Subject Headings

Humans; Anemia, Sickle Cell; Male; Female; Patient Satisfaction; Pain Management; Adult; Emergency Service, Hospital; Pain Measurement; Clinical Protocols; Body Weight; Young Adult

PubMed ID

40019423

Volume

51

Issue

4

First Page

626

Last Page

635

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