Association between Prenatal One-Hour Glucose Challenge Test Values and Delivery Mode in Nondiabetic, Pregnant Black Women

Document Type

Article

Publication Date

1-1-2015

Publication Title

J Pregnancy

Keywords

Adolescent, Adult, African Americans, Body Mass Index, Cesarean Section, Diabetes, Gestational, Female, Glucose Tolerance Test, Humans, Logistic Models, Michigan, Parity, Pregnancy, Pregnancy Outcome, Prenatal Care, Prospective Studies, Risk Factors, Young Adult

Abstract

OBJECTIVE: We examined the association between 1-hour glucose challenge test (GCT) values and risk of caesarean section.

STUDY DESIGN: A prospective cohort study recruited 203 pregnant Black women to participate. At ~28 weeks of gestation, participants underwent a routine 1-hour 50 g GCT to screen for gestational diabetes mellitus. Logistic regression was used to examine the association between 1-hour GCT value and delivery mode.

RESULTS: Of the 158 participants included, 53 (33.5%) delivered via C-section; the majority (n = 29; 54.7%) were nulliparous. Mean 1-hour GCT values were slightly, but not significantly, higher among women delivering via C-section; versus vaginally (107.8 ± 20.7 versus 102.4 ± 21.5 mg/dL, resp.; P = 0.13). After stratifying by parity and adjusting for maternal age, previous C-section, and prepregnancy body mass index, 1-hour GCT value was significantly associated with increased risk of C-section among parous women (OR per 1 mg/dL increase in GCT value = 1.05; 95% CI OR: 1.00, 1.05; P = 0.045).

CONCLUSION: Even slightly elevated 1-hour 50 g GCT values may be associated with delivery mode among parous Black women.

Medical Subject Headings

Adolescent; Adult; African Americans; Body Mass Index; Cesarean Section; Diabetes, Gestational; Female; Glucose Tolerance Test; Humans; Logistic Models; Michigan; Parity; Pregnancy; Pregnancy Outcome; Prenatal Care; Prospective Studies; Risk Factors; Young Adult

PubMed ID

26101668

Volume

2015

First Page

835613

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