Development of Hepatocellular Carcinoma in Type IB Abernethy Malformation

Authors

Fateh Ahmad, Henry Ford HealthFollow
Vatsal Khanna, Henry Ford HealthFollow
Neil Al-Saidi, Henry Ford HealthFollow
Leonid Shamban, Henry Ford HealthFollow

Recommended Citation

Ahmadi F, Khanna V, Al-Saidi N, Shamban L. Development of Hepatocellular Carcinoma in Type IB Abernethy Malformation. ACG Case Rep J. 2026;13(2):e02021.

Document Type

Article

Publication Date

2-1-2026

Publication Title

ACG Case Rep J

Keywords

Abernethy malformation; congenital extrahepatic portosystemic shunt; hepatic neoplasm; hepatocellular carcinoma; stereotactic body radiation therapy

Abstract

Abernethy malformation, a congenital extrahepatic portosystemic shunt, allows portal venous blood to bypass the liver and has been shown to predispose patients to hepatic tumors. We present a 29-year-old man with Type IB Abernethy malformation diagnosed in infancy who developed hepatocellular carcinoma in a noncirrhotic liver. Surgical resection, the standard curative therapy, was not feasible due to complex vascular anatomy, and he was treated with stereotactic body radiation therapy. Post-treatment imaging demonstrated sustained improvement. This case highlights the malignant potential of congenital portosystemic shunts and the importance of long-term surveillance.

PubMed ID

41728251

Volume

13

Issue

2

First Page

02021

Last Page

02021