Small Bowel Adenocarcinoma Masquerading as Crohn's Disease

Authors

Se Yeon Kim, Henry Ford HealthFollow
Brandon Wiggins, Henry Ford HealthFollow
Daniel Ramirez, Henry Ford HealthFollow
Mark J. Minaudo, Henry Ford HealthFollow

Recommended Citation

Kim SY, Wiggins B, Ramirez D, and Minaudo M. Small Bowel Adenocarcinoma Masquerading as Crohn's Disease. Cureus 2025;17(9):e92797.

Document Type

Article

Publication Date

9-1-2025

Publication Title

Cureus

Keywords

crohn’s disease (cd); gastroenterology tumor; ileocecal region; small bowel adenocarcinoma (sba); small bowel tumors

Abstract

Small bowel adenocarcinoma (SBA) is a rare gastrointestinal malignancy, with the majority of cases seen in the duodenum. SBA often poses a diagnostic challenge due to its non-specific presentation. A 46-year-old female smoker presented with a 6-week history of persistent abdominal pain and nausea. The initial workups, including computed tomography and colonoscopy, demonstrated evidence of suspected Crohn's disease (CD). The histopathology of an ileocecal valve ulcer revealed invasive adenocarcinoma. Our case highlights the necessity of considering SBA in the differential diagnosis for patients exhibiting symptoms similar to Crohn's disease, as delays in diagnosis and treatment may result in disease progression and complications, including small bowel obstruction.

PubMed ID

41122556

Volume

17

Issue

9

First Page

92797

Last Page

92797