Recommended Citation
Lenhart A, Meighani A, Hassan M, and Gordon SC. Hepatitis C Virus-Associated Aortitis Caused by Type I Cryoglobulins. ACG Case Rep J 2017; 4:e114.
Document Type
Article
Publication Date
1-1-2017
Publication Title
ACG Case Rep J
Abstract
Chronic hepatitis C virus infection (HCV) can present with cryoglobulinemic vasculitis, which is primarily associated with type II/III cryoglobulins. Type I cryoglobulins are usually seen in lymphoproliferative disease, and large vessel involvement with this type of vasculitis is rare. A 70-year-old man with chronic HCV presented with abdominal pain, leukocytosis, and rash. Computed tomography angiography showed thickening of the abdominal aorta consistent with large-vessel vasculitis. He was found to have type I cryoglobulinemia and was treated with corticosteroids and ledipasvir/sofosbuvir with rapid resolution of his aortitis. This case emphasizes the need to recognize HCV as a potential etiology of large-vessel vasculitis.
PubMed ID
29090238
Volume
4
First Page
114