Anatomy, Abdomen and Pelvis, Sphincter of Oddi (Hepatopancreatic Sphincter)
Ahmed A, Zuchelli T. Anatomy, Abdomen and Pelvis, Sphincter of Oddi (Hepatopancreatic Sphincter). StatPearls 2020; .
First described by Ruggero Oddi in 1887, the sphincter of Oddi (SO) is a smooth muscle valve located in the second portion of the duodenum. It serves to regulate the flow of hepatic and pancreatic substances into the small intestines. Although its function seems simple, it represents a great example of how smooth muscle can be under the regulation by hormones and other signals. The SO serves many purposes in medicine and is often traversed in procedures such as endoscopic retrograde cholangiopancreatography (ERCP). This sphincter may also become dysfunctional at times requiring either medical or surgical intervention.