ROLE OF ENDOSCOPIC ULTRASOUND AND PROGRESSION OF PANCREATIC CYSTS IN SOLID ORGAN TRANSPLANT PATIENTS
Recommended Citation
Samad M, Kostecki P, Nabaty R, Faisal MS, Jamali T, Chaudhary A, Youssef R, Zuchelli T, Singla S, Piraka C. ROLE OF ENDOSCOPIC ULTRASOUND AND PROGRESSION OF PANCREATIC CYSTS IN SOLID ORGAN TRANSPLANT PATIENTS. Gastrointest Endosc 2024; 99(6):AB933.
Document Type
Conference Proceeding
Publication Date
6-1-2024
Publication Title
Gastrointest Endosc
Abstract
Introduction: Given the increased frequency of imaging in solid organ transplant (SOT) candidates, the incidence of pancreatic cysts in this population has risen. Neither definitive guidelines nor convincing evidence for routine evaluation and surveillance of pancreatic cysts in these patients has been established. The aim of this study was to explore the clinical yield of EUS in the evaluation and management of pancreatic cysts in SOT patients. Methods: This was designed as a single center retrospective cohort study. SOT recipients who had imaging findings of pancreatic cysts from 2015-2023 were identified using ICD-9/10CM diagnosis codes. These patients were then cross-referenced with an endoscopic procedure database to identify SOT recipients who underwent EUS. Patients were divided into two groups, one that received EUS within one year of transplant and one that did not. Primary outcomes included progression of cysts, development of new cysts, worrisome features identified by Fukuoka classification, and change in management following transplant. Secondary outcomes included diagnosis of pancreatic cancer and surgery for cyst. Results: A total of 136 solid organ transplant patients were identified with pancreatic cysts from 2013 to 2023. 46 (34%) had identified worrisome features after transplant. 7 patients (5%) had a mean increase of at least 5 mm annually and/or an increase in number of cysts as evidenced by CT or MRI. There was a statistically significant relationship between increase in size and new cysts identified in SOT patients(Pearson Chi-Square value of 4.165 , p<0.05). Additionally, EUS did not have an association with increase in pancreatic cyst size, cancer diagnosis, or worrisome features (Table 1). Conclusion: Progression of pancreatic cyst size, development of high-risk features, and increase in new cysts in SOT patients is similar when compared to general population studies of patients without SOT 1,2 . Additionally, EUS did not have an association with progression of nonmalignant cysts in SOT patients.
Volume
99
Issue
6
First Page
AB933
