Cutaneous Metastases Without a Known Primary: A Clinical Conundrum

Authors

Dhairya Gor, Henry Ford HealthFollow
Bipin Ghimire, Henry Ford HealthFollow
Omar Abbas, Henry Ford HealthFollow
Maria Diab, Henry Ford HealthFollow

Recommended Citation

Gor D, Ghimire B, Abbas O, and Diab M. Cutaneous Metastases Without a Known Primary: A Clinical Conundrum. Cureus 2025;17(5):e83591.

Document Type

Article

Publication Date

5-1-2025

Publication Title

Cureus

Keywords

adenocarcinoma; carcinoma of unknown primary; cutaneous metastases of unknown primary; diagnostic and therapeutic challenge; solitary skin metastases

Abstract

Cutaneous metastases of unknown primary are a relatively rare clinical entity, presenting unique diagnostic and management challenges despite advancements in diagnostic techniques. Due to their rarity, management often requires an individualized, multidisciplinary approach. These metastases are typically associated with a poor prognosis. Clinicians should consider this diagnosis when evaluating skin lesions, as early recognition is crucial for optimal outcomes. Here, we present the case of a 56-year-old male with a skin lesion on his left leg, highlighting the diagnostic complexities and management strategies associated with cutaneous metastases of unknown primary.

PubMed ID

40476116

Volume

17

Issue

5

First Page

83591

Last Page

83591