Roentgenograms are frequently inadequate in the detection of early osseous metastases. Isotope bone scan is a more sensitive diagnostic procedure. Reported here are findings on 40 patients with known or suspected osseous involvement using the short-lived radionuclide 18F. Comparison with standard roentgenograms and clinical follow-up demonstrated 11 early detections. 18F was found to be a very suitable agent for isotope bone scanning. Ilustrative cases are presented
Gatesi, R. A.; Vulpetti, A. T.; Kosnik, T. L.; Tucker, W. G.; and Talley, R. W.
"The Clinical Use of Fluorine18 in Bone Scanning,"
Henry Ford Hospital Medical Journal
: Vol. 17
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol17/iss2/6