This study documented the fact that recurrent episodes of small bowel obstruction were not uncommon (38%) in a review of 120 patients who underwent lysis of adhesions or lysis of adhesions and Noble Plication. A laboratory experiment using dogs was constructed to compare dextran to a combined promethazine-dexamethasone regimen for the prevention of adhesion formation in the immediate post-operative period. Dextran was completely ineffective in preventing adhesion reformation. Meticulous surgical technique remains the single most important factor in adhesion prevention.
Cromwell, T. A. and Ponka, Joseph L.
"The Prevention of Recurrent Peritoneal Adhesions: A Clinical and Laboratory Investigation,"
Henry Ford Hospital Medical Journal
: Vol. 18
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol18/iss4/3