Henry Ford Hospital Medical Journal


Systemic immune status was studied in 86 idiopathic ulcerative colitis patients. Quantitation of the major serum immunoglobulins (IgG, IgA and IgM) and qualitation for specific enteropathogens (bacterial and viral) associated with the immunoglobulins are correlated with the severity and duration of the disease. The studies demonstrate the immunologic competence of these patients to respond to a variety of infections with normal activity and hyperactivity. In addition, systemic complications associated with ulcerative colitis, particularly liver involvement, are reflected in the immunologic studies.