Heterotopic transplantation of the dog heart to an abdominal location is a satisfactory experimental model for the study of immunosuppression. Rejection signs are readily detected by palpation and electrocardiographic monitoring.
Taber, Rodman; Kouno, Nobuatsu; and Simon, Jorge
"Intra-abdominal Heterotopic Transplantation of the Canine Heart,"
Henry Ford Hospital Medical Journal
: Vol. 19
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol19/iss4/2