C-Reactive Protein: Potential Significance of Quantitation in Patients with Chronic Diseases

Authors

Hajime Hayashi
Gerald A. LoGrippo

Abstract

Serum C-reactive protein (CRP) levels in 351 patients with certain chronic diseases were assayed by a micro-double immunodiffusion technique developed and used in this hospital. Elevation of CRP values and severity of disease were evident in the following clinical entities: 31 of 54 patients (57%) with liver cirrhosis; 122 of 204 (60%) hepatitis patients; 34 of 52 (65%) patients with gastro-intestinal surgery; 8 of 21 (38%) uremic patients; and all of 20 patients with renal transplantation. There was good correlation between markedly elevated serum CRP values and degree of inflammation and/or physiologic stress during clinical course and recovery.

Recommended Citation

Hayashi, Hajime and LoGrippo, Gerald A. (1972) "C-Reactive Protein: Potential Significance of Quantitation in Patients with Chronic Diseases," Henry Ford Hospital Medical Journal : Vol. 20 : No. 2 , 91-96.
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol20/iss2/7