Henry Ford Hospital Medical Journal


The hypertension which follows an intrinsic increase in pulmonary vascular resistance may be easily diagnosed by utilizing current catheterization and radiologic techniques. The real challenge is establishing a rational etiology in a given case before final pathological examination. Data from 33 proven cases are presented in an attempt to show that most ofthe proposed etiologic concepts may be represented in a large clinical series. Congenital and familial factors, multiple pulmonary embolization with resulting vasospastic sequela, arteritis, and degenerative states, were encountered, together with such specific clinical entities as scleroderma and systemic lupus erythematosus. Because the term "Primary Pulmonary Hypertension" implies only the exclusion of volume overloaded states, it requires further etiologic clarification.