A woman with medullary carcinoma of the thyroid and a past history of breast cancer was found to have metastatic bone lesions. It was initially assumed that this was due to recurrent breast carcinoma, but bone biopsy revealed medullary carcinoma of thyroid origin. Although clinical bone metastasis is a rare event in patients with medullary carcinoma, quite clearly such an occurrence is possible. Medullary carcinoma should be considered in the differential diagnosis of patients with metastatic bone lesions.
Stoffer, Sheldon S.; Kobernick, Sidney D.; Zirkin, Richard M.; Hamburger, Stuart W.; and Harold, Susan E.
"Medullary Carcinoma of the Thyroid with Bone Metastasis,"
Henry Ford Hospital Medical Journal
: Vol. 30
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol30/iss2/9