We studied the effect of tetracycline on bile acid pool composition in a human subject. A dosage of 250 mg (qid) of tetracycline for one week completely eliminated deoxycholic and lithocholic acid from the pool. Tetracycline may be of value for limiting the build-up of lithocholic acid in patients who are treated with chenodeoxycholic acid to dissolve gallstones.
Waldbaum, Jerome R.; Beher, William T.; Priest, Robert J.; and Stradnieks, Sofia
"Effects of Tetracycline on Fecal Bile Acid Pool Composition in a Human: A Preliminary Report,"
Henry Ford Hospital Medical Journal
: Vol. 30
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol30/iss3/12