Patients presenting with esophageal disorders often describe what can be called a "first-bite syndrome." The condition can be discerned by its characteristic clinical features. It may be a variant of diffuse esophageal spasm. While in a majority of patients it is a benign functional disturbance, it can be a harbinger of carcinoma. When of functional origin, it is amenable, in most cases, to relatively simple medical management.
Haubrich, William S.
"The First-Bite Syndrome,"
Henry Ford Hospital Medical Journal
: Vol. 34
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol34/iss4/12