Primary ovarian failure in adolescence is uncommon. This report depicts such a case in a 17 1/2-year old girl whose investigation revealed elevations in the follicle-stimulating hormone and luteinizing hormone levels in association with a low estrogen level. The blood leukocyte chromosome analysis with Giemsa banding revealed a 46,XX chromosomal complement. Pelvic ultrasound disclosed a rudimentary uterus and a small left ovary. Hormonal replacement has resulted in advancement of secondary sexual characteristics and monthly withdrawal bleeding.
Caison-Sorey, T. Jann
"Ovarian Failure in a Chromosomally Competent Adolescent Female: A Case Report,"
Henry Ford Hospital Medical Journal
: Vol. 36
Available at: https://scholarlycommons.henryford.com/hfhmedjournal/vol36/iss4/8