Recommended Citation
Parmar V, Bayya M, and Kak V. Herpes Simplex Virus Causing Necrotizing Granulomatous Lymphadenitis. Cureus 2022; 14(3):e23709.
Document Type
Article
Publication Date
3-1-2022
Publication Title
Cureus
Abstract
Localized necrotizing granulomatous lymphadenitis (GLA) is a very rare presentation of herpes simplex virus (HSV) infection. We are reporting a case that required multidisciplinary expertise to confirm the diagnosis and effectively treat the patient. Our patient had a recent diagnosis of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) and presented with hematuria and palpable inguinal lymph nodes. Affirmative diagnosis required a core biopsy of the lymph node with immunochemistry staining and polymerase chain reaction (PCR) testing. This case reviews the unusual presentation of an HSV infection and emphasizes the importance of maintaining a high index of suspicion for infection when treating an immunocompromised patient with persistent symptoms.
PubMed ID
35505723
Volume
14
Issue
3
First Page
23709
Last Page
23709