Gut microbiome and its clinical implications: exploring the key players in human health
Recommended Citation
Koneru S, Thiruvadi V, and Ramesh M. Gut microbiome and its clinical implications: exploring the key players in human health. Curr Opin Infect Dis 2023.
Document Type
Article
Publication Date
10-1-2023
Publication Title
Current opinion in infectious diseases
Abstract
PURPOSE OF REVIEW: The human gut harbors a diverse community of microorganisms known as the gut microbiota. Extensive research in recent years has shed light on the profound influence of the gut microbiome on human health and disease. This review aims to explore the role of the gut microbiome in various clinical conditions and highlight the emerging therapeutic potential of targeting the gut microbiota for disease management.
RECENT FINDINGS: Knowledge of the influence of gut microbiota on human physiology led to the development of various therapeutic possibilities such as fecal microbiota transplant (FMT), phage therapy, prebiotics, and probiotics. Recently, the U.S. FDA approved two FMT products for the treatment of recurrent Clostridioides difficile infection with ongoing research for the treatment of various disease conditions.
SUMMARY: Advancement in the knowledge of the association between gut microbiota and various disease processes has paved the way for novel therapeutics.
Medical Subject Headings
Humans; Gastrointestinal Microbiome; Disease Management; Fecal Microbiota Transplantation; Phage Therapy; Probiotics
PubMed ID
37593952
ePublication
ePub ahead of print
Volume
36
Issue
5
First Page
353
Last Page
359
