Multidrug-resistant microorganisms colonizing lower extremity wounds in patients in a tertiary care hospital, Lima, Peru

Document Type

Article

Publication Date

10-1-2017

Publication Title

Am J Trop Med Hyg

Abstract

Multidrug-resistant organism (MDRO) infections cause high morbidity and mortality, and high costs to patients and hospitals. The study aims were to determine the frequency of MDRO colonization and associated factors in patients with lower-extremity wounds with colonization. A cross-sectional study was designed during November 2015 to July 2016 in a tertiary care hospital in Lima, Peru. A wound swab was obtained for culture and susceptibility testing. MDRO colonization was defined if the culture grew with methicillin-resistant Staphylococcus aureus, vancomycin-resistant enterococci, and/or extended spectrum beta-lactamase (ESBL) microorganisms. The frequency of MDRO wound colonization was 26.8% among the 97 patients enrolled. The most frequent MDRO obtained was ESBL-producing Escherichia coli, which was significantly more frequent in chronic wounds versus acute wounds (17.2% versus 0%, P < 0.05). Infection control measures should be implemented when patients with chronic lower-extremity wounds are admitted.

Medical Subject Headings

Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Drug Resistance, Multiple, Bacterial; Female; Humans; Lower Extremity; Male; Middle Aged; Peru; Prevalence; Staphylococcal Infections; Tertiary Care Centers; Wounds and Injuries

PubMed ID

28722595

Volume

97

Issue

4

First Page

1045

Last Page

1048

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