Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed
Recommended Citation
Syed H, Bachuwa G, Upadhaya S, Abed F. Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed. BMJ Case Rep. 2016 Feb 24;2016. pii: bcr2015213967.
Document Type
Article
Publication Date
2-24-2016
Publication Title
BMJ Case Rep
Abstract
Interstitial lung disease (ILD) is a rare adverse effect of nitrofurantoin and can range from benign infiltrates to a fatal condition. Nitrofurantoin acts via inhibiting the protein synthesis in bacteria by helping reactive intermediates and is known to produce primary lung parenchymal injury through an oxidant mechanism. Stopping the drug leads to complete recovery of symptoms. In this report, we present a case of nitrofurantoin-induced ILD with the recovery of symptoms and disease process after stopping the drug.
Medical Subject Headings
Adult; Anti-Infective Agents, Urinary; Diagnosis, Differential; Female; Humans; Lung Diseases, Interstitial; Nitrofurantoin
PubMed ID
26912767
Volume
2016
First Page
bcr2015213967