Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed
Syed H, Bachuwa G, Upadhaya S, Abed F. Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed. BMJ Case Rep. 2016 Feb 24;2016. pii: bcr2015213967.
BMJ Case Rep
Interstitial lung disease (ILD) is a rare adverse effect of nitrofurantoin and can range from benign infiltrates to a fatal condition. Nitrofurantoin acts via inhibiting the protein synthesis in bacteria by helping reactive intermediates and is known to produce primary lung parenchymal injury through an oxidant mechanism. Stopping the drug leads to complete recovery of symptoms. In this report, we present a case of nitrofurantoin-induced ILD with the recovery of symptoms and disease process after stopping the drug.
Medical Subject Headings
Adult; Anti-Infective Agents, Urinary; Diagnosis, Differential; Female; Humans; Lung Diseases, Interstitial; Nitrofurantoin