Title

Nitrofurantoin-induced interstitial pneumonitis: albeit rare, should not be missed.

Document Type

Article

Publication Date

2-24-2016

Publication Title

BMJ Case Rep

Abstract

Interstitial lung disease (ILD) is a rare adverse effect of nitrofurantoin and can range from benign infiltrates to a fatal condition. Nitrofurantoin acts via inhibiting the protein synthesis in bacteria by helping reactive intermediates and is known to produce primary lung parenchymal injury through an oxidant mechanism. Stopping the drug leads to complete recovery of symptoms. In this report, we present a case of nitrofurantoin-induced ILD with the recovery of symptoms and disease process after stopping the drug.

Medical Subject Headings

Adult; Anti-Infective Agents, Urinary; Diagnosis, Differential; Female; Humans; Lung Diseases, Interstitial; Nitrofurantoin

PubMed ID

26912767

Volume

2016

First Page

bcr2015213967

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