Recommended Citation
Chao S, Al-Saheli ZI, Zhao W, Ghosh S, and Dabak V. ALK-Positive Anaplastic Large Cell Lymphoma Associated With Hemophagocytic Lymphohistiocytosis. Cureus 2023; 15(7):e41427.
Document Type
Article
Publication Date
7-1-2023
Publication Title
Cureus
Abstract
Hemophagocytic lymphohistiocytosis (HLH) has been rarely reported as a complication of anaplastic large cell lymphoma (ALCL), especially in the adult population. We herein present a case of a young woman who presented with multiorgan failure and disseminated intravascular hemolysis and was later found to have ALCL-associated HLH. We also review the current literature on ALCL-associated HLH in adult patients, with their respective treatments and outcomes. We discuss the challenges associated with the diagnosis of lymphoma in the setting of HLH and multiorgan failure. Further, given its high mortality rates, we highlight the importance of promptly identifying and treating the underlying etiology of HLH.
PubMed ID
37426397
Volume
15
Issue
7
First Page
41427
Last Page
41427
