Hepatotoxicity induced by MK-677

Authors

Era Cobani, Henry Ford HealthFollow
Md Shahnoor Amin, Henry Ford HealthFollow
Muneer F. Hasso, Henry Ford HealthFollow
Lalathaksha Kumbar, Henry Ford HealthFollow

Recommended Citation

Cobani E, Amin MS, Hasso M, and Kumbar L. Hepatotoxicity induced by MK-677. BMJ Case Rep 2025;18(7).

Document Type

Article

Publication Date

7-17-2025

Publication Title

BMJ Case Rep

Abstract

MK-677, a growth hormone secretagogue, is gaining popularity among performance-enhancing supplements. While its side effects include oedema, increased appetite and muscle pain, reports of hepatotoxicity are scarce. Here we present the case of an otherwise healthy man in his early 30s, who developed transaminitis after consuming MK-677 for 2 months before presentation. Liver function tests eventually returned to normal limits after stopping the supplement.

Medical Subject Headings

Humans; Male; Chemical and Drug Induced Liver Injury; Adult; Dietary Supplements; Liver Function Tests

PubMed ID

40675653

Volume

18

Issue

7